Table 2.

Brain levels (mean ± standard deviation) of estrogens and androgens in female cases neuropathologically characterized as normal and AD, and grouped by age: all cases (56–94 years), 60–79 years, and ≥80 years.

		Sample size	Age, years	PMI, hours	T, ng/g WT	DHT, ng/g WT	E1, ng/g WT	E2, ng/g WT
All cases	NOR	12	81.3 ± 2.5	5.9 ± 0.6	0.65 ± 0.12	0.12 ± 0.02	1.11 ± 0.27	0.12 ± 0.03
	AD	32	74.3 ± 1.6*	5.1 ± 0.4	0.54 ± 0.07	0.13 ± 0.01	0.57 ± 0.2*	0.07 ± 0.02
60−79 y	NOR	6	71.3 ± 2.7	6.1 ± 0.8	0.63 ± 0.17	0.11 ± 0.03	1.04 ± 0.4	0.08 ± 0.02
	AD	24	71.3 ± 1.3	5.1 ± 0.4	0.57 ± 0.08	0.14 ± 0.01	0.6 ± 0.2	0.07 ± 0.01
≥80 y	NOR	6	90.0 ± 1.7	5.7 ± 0.8	0.84 ± 0.12	0.14 ± 0.04	1.53 ± 0.29	0.19 ± 0.04
	AD	7	84.6 ± 1.6*	4.2 ± 1.4	0.27 ± 0.11*	0.07 ± 0.03	0.3 ± 0.26*	0.04 ± 0.07*

^*p < 0.05 relative to age-matched neuropathologically normal (NOR) group