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. Author manuscript; available in PMC: 2011 Oct 15.
Published in final edited form as: Free Radic Biol Med. 2010 Jul 16;49(7):1212–1220. doi: 10.1016/j.freeradbiomed.2010.07.007

Fig. 3.

Fig. 3

Caffeine regulates tau phosphorylation in cholesterol-fed rabbits in a dose-dependent manner. Western blots (a) and densitometric analyses (b) show that caffeine at 30 mg/day but not at 0.5 mg/day reduces tau phosphorylation in hippocampus from rabbits fed a 2% cholesterol-enriched diet. Tau phosphorylation is detected by PHF-1 and CP13 antibodies. **p<0.01 versus controls, #p<0.05 versus rabbits fed with 2% cholesterol diet.