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. 2010 Aug;60(4):272–281.

Table 1.

Chrm2 genotype and phenotype strain distribution patterns

Responses at 30 min after injection of 0.1 mg.kg oxotremorine
Strain Chrm2 genotypea Startle amplitudeb PPIc Hypothermia (°C) Tremord Salivationd Bradycardia (bpm)d
BALB/cByJ BALB/cByJ high impaired −4.4 ± 0.4 1.5 ± 0.2 1.5 ± 0.2 −98 ± 22
C57BL/6J C57BL/6J low normal −4.0 ± 0.6 1.8 ± 0.2 1.2 ± 0.3 −151 ± 39
CXB2 C57BL/6J not tested not tested −6.3 ± 0.5 1.8 ± 0.2 1.8 ± 0.2 −86 ± 69
CXB3 BALB/cByJ low impaired −5.1 ± 0.6 2.0 ± 04 0.8 ± 0.2 −190 ± 22
CXB5 BALB/cByJ not tested not tested −3.7 ± 0.6 2.0 ± 0.3 1,4 ± 0.4 −157 ± 21
CXB6 BALB/cByJ high normal −4.5 ± 0.4 1.9 ± 0.1 1.3 ± 0.2 −221 ± 44
CXB9 BALB/cByJ low impaired −6.5 ± 0.5 0.7 ± 0.2 0.6 ± 0.2 −38 ± 23
CXB12 C57BL/6J high impaired −4.9 ± 0.7 1.8 ± 0.2 0.3 ± 0.2 −81 ± 15
a

Data from Figure 1

b

Data from Figures 4,5; relative amplitudes

c

Data from Figures 4,5 (10 dB)

d

Data from Figures 2,3