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. Author manuscript; available in PMC: 2010 Aug 31.
Published in final edited form as: Adv Exp Med Biol. 2010;703:105–125. doi: 10.1007/978-1-4419-5635-4_8

Fig. 7.

Fig. 7

(a) Illustration of the proposed biological role of ABCA4. The left part of the diagram represents a ROS disk with a functional ABCA4, whereas the right part represents a ROS disk with an inactive ABCA4. Hexagons with carbon backbone denote all-trans-retinal (black) and all-trans-retinol (red). RDH: all-trans-retinol dehydrogenase 8. RPE: retinal pigment epithelium. See text for the description of the mechanism. (b) Schematic representations of rod and cone outer segments. Cone disks are open structures