Fig. 3.
Effect of reduced extraluminal O2 tension on dilation of isolated skeletal muscle arterioles perfused with erythrocytes. Isolated arterioles were exposed to either extraluminal normoxia (room air, Po2 = 145 ± 2 mmHg) or reduced O2 tension (Po2 = 18 ± 3 mmHg) and perfused with buffer containing well-oxygenated erythrocytes from either healthy humans (n = 7) or humans with DM2 (n = 6, HbA1c = 8.3 ± 0.8). Values are means ± SE. *Different from value during normoxia. †Different from vessels perfused with erythrocytes of humans with DM2 (P < 0.01).