Table 2.
Results of ER assays on NPs and NPEs.
Chemical | Assay | EC50 (μM) | R2 | EMax | p-value |
---|---|---|---|---|---|
Nonylphenol (linear) 104–40–5 |
trans -ERα | 11 | 0.77 | 8.3 | 0.29 |
cis-ERE | 4.3 | 0.55 | 2.7 | 0.096 | |
Nonylphenol (branched) 84852–15–3 |
trans -ERα | 0.68 | 0.91 | 12 | 0.0049 |
cis-ERE | 0.61 | 0.092 | 5.4 | 4.9E-5 | |
Tergitol NP-9 127087–87–0 |
trans -ERα | 5.7 | 0.86 | 4.8 | 0.18 |
cis-ERE | 5.6 | 0.96 | 2.1 | 0.042 | |
Igepal CO–210 68412–54–4 |
trans -ERα | 2.5 | 0.89 | 8.5 | 0.19 |
cis-ERE | 14 | 0.96 | 6.5 | 2.1E-11 |