Fig. 3.

A plot of conduction speed versus fraction of normal gap-junctional conductance for several nonephaptic models and levels of resolution. The coarse macroscale simulations incorrectly predict the value of gap-junctional conductance at which propagation block occurs. The fine macroscale simulations fail to predict propagation block at all. The macroscale simulations with one node per myocyte exhibit remarkable agreement with the microscale and adaptive multiscale simulations over a wide range of gap-junctional coupling levels.