Table 1.

Vorinostat-induced yH2AX foci in normal (HFS) and transformed (LNCaP, A549) cells

Measurement	HFS		LNCaP		A549
	No Tx	HDACi	No Tx	HDACi	No Tx	HDACi
Total cells, n	423	143	132	286	208	100
Foci per nucleus,* %	0.9	4.8	0.02	15.3	2.7	21.7

*Ratio of phospho-H2AX area over DAPI area was measured by MetaMorph 7.6.5 (Molecular Devices). Each value in table was obtained by examining at least 100 cells.