Fig. 3.

(A) Neural activity in the dorsal anterior cingulate cortex (dACC) during social exclusion (vs. inclusion) that correlated positively with inflammatory responses to the Trier Social Stress Test (TSST), as indexed by changes in levels of a soluble receptor for tumor necrosis factor-α (sTNFαRII). (B) Scatterplot showing the relation between mean activity in the dACC cluster (thresholded at P < 0.001, 20 voxels) and sTNFαRII responses to the TSST. Greater activity in the dACC was significantly associated with greater sTNFαRII responses to the TSST (n = 31).