Fig. 4.
The effects of NBO (95% O2) and nNOS inhibitor (7-NI) treatments on the formation of 3-nitrotyrosine (3-NT) in ischemic cortex at 30 minutes after MCAO onset. 7-NI (25 mg/kg) was intraperitoneally injected 20 minutes before the onset of ischemia. Compared with normoxic (30% O2) group, both NBO and 7-NI significantly suppressed the formation of 3-NT. Data were expressed as Mean ± S.D. * P<0.05, versus normoxic group, n=4.