Table 1. Spontaneous Calcium Release Events in Ventricular Myocytes and Purkinje Cells.
| Cells with SCaEs | SCaEs Per Cell | |||||||
|---|---|---|---|---|---|---|---|---|
| - ISO | +ISO | -ISO | + ISO | |||||
| 1 Hz | 3 Hz | 5 Hz | 1 Hz | 1 HZ | 3 Hz | 5 Hz | 1 Hz | |
| WT VM | 0% (15) | 7% (15) | 7% (15) | 14% (7) | 0 ± 0 (15) | 0.07 ± .07 (15) | 0.07 ± .07 (15) | 0.14 ± .14 (7) |
| WT PC | 10% (10) | 30% (10) | 30% (10) | 57% (7) | 0.10 ± .10 (10) | 0.40 ± .22 (10) | 0.40 ± .22 (10) | 3.00 ± 1.38 (7) |
| MUT VM | 22% (41) | 24% (41) | 29% (41) | 40% (10) | 0.29 ± .09 (41) | 0.37 ± .11 (41) | .34 ± .09 (41) | 1.10 ± .48 (10) |
| MUT PC | 52% (29) | 62% (29) | 62% (29) | 90% (10) | 1.07 ± .32 (29) | 1.72 ± .36 (29) | 1.65 ± .36 (29) | 12.2 ± 1.48 (10) |
Data are shown as percentage of of cells with spontaneous Ca2+ release events (SCaEs) and the mean ± SEM SCaEs/cell at each pacing frequency. The number of cells studied for each condition are shown in parentheses. WT, wild type; MUT, mutant; VM, ventricular myocyte; PC, Purkinje cell; ISO, isoproterenol.