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. 2010 Jun 29;285(35):26806–26814. doi: 10.1074/jbc.M110.109975

FIGURE 5.

FIGURE 5.

Comparison of the single-channel kinetics of TRPM2, TRPM8, and M2-M8P. A–C show representative traces from inside-out patches from cells transfected with wild-type TRPM8, wild-type TRPM2, or M2-M8P, respectively, along with an analysis of the open times. The number of openings was attributed to bins of widths shown on the abscissa. Mono- or biexponential fits of the histograms yielded the open times (τopen) indicated for each panel. The holding potential was −60 mV. Data were sampled from a total of 12 patches. c, closed; o, open.