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Sequence alignments of the citrate-binding domain of human ATP-citrate lyase with similar sequences in E. coli succinyl-CoA synthetase, Methylobacterium extorquens AM1 malyl-CoA synthetase, and H. thermophilus TK-6 citryl-CoA synthetase (49). The citrate-binding loop and Arg-379 of ATP-citrate lyase are highlighted with arrowheads.
