TABLE 2.
Simultaneous knockdown of SIN3 190 and SIN3 220 results in lethality
Multiple independent UAS-190,220RNAi/UAS-190,220RNAi fly lines were crossed with the tub-GAL4/Sb driver line, and the progeny were analyzed and counted. All adult progeny had stubble bristles, indicating that they did not express the GAL4 activator required for SIN3 knockdown. The number of flies reported represents the total number from two independent parental crosses for each line.
| RNAi line | Number of adults observed |
|
|---|---|---|
| UAS-190,220RNAi/tub-GAL4 | UAS-190,220RNAi/Sb | |
| UAS-190,220RNAi 4 | 0 | 362 |
| UAS-190,220RNAi 16 | 0 | 447 |
| UAS-190,220RNAi 17a | 0 | 374 |
| UAS-190,220RNAi 18 | 0 | 575 |