Skip to main content
. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Nat Neurosci. 2010 May 9;13(6):723–730. doi: 10.1038/nn.2546

Figure 6.

Figure 6

Residuals of model fitting reveal input patterns missing in the VSN data set. (a) The AOB responses identified as cluster 10 showed excitation to multiple members of the pregnanolone class of steroids at 10 μM, but we did not observe such a response profile in VSNs at 10 μM. Investigation of VSN responses in a separate dataset revealed broad pregnanolone responses, shown on the log-linear plot, but only at concentrations > 10 μM. These neurons tended also to respond to 1:100 BALB/c female urine. The gray shaded region indicates the concentration range sampled in the main VSN dataset used for clustering analysis. (b) Cluster analysis of linear-nonlinear model fit residuals indicated 3 common patterns unaccounted for in the VSN input population (labeled A-C). Heat map indicates the power in the residuals for each of the 12 sulfated steroids, measured in terms of the ratio between the value and uncertainty (z-score).