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. Author manuscript; available in PMC: 2010 Aug 31.
Published in final edited form as: Neurobiol Dis. 2005 Jun–Jul;19(1-2):200–207. doi: 10.1016/j.nbd.2004.12.015

Fig. 4.

Fig. 4

Reduced HCN1 protein levels after ‘febrile’ seizures are attributable to lower mRNA levels. (A) Representative photomicrographs and quantitative analysis of HCN1 mRNA in hippocampal CA1 and CA3 a week after the seizures reaffirm diminished expression of this channel isoform (Brewster et al., 2002). (B) HCN2 mRNA levels are greater in the Feb group, as seen in the representative hippocampal photomicrographs and the analysis. However, increased mRNA expression is not reflected in increased protein levels (Fig. 3C), potentially because of increased channel turnover. * Denotes significant difference from the control group.