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. Author manuscript; available in PMC: 2010 Aug 31.
Published in final edited form as: J Neural Eng. 2009 Mar 13;6(2):026005. doi: 10.1088/1741-2560/6/2/026005

Figure 6.

Figure 6

Immunohistochemistry for neuronal markers (NeuN, green; neurofilament, red) reveals an initial injury response in which neuronal soma are distanced from the probe, and neurofilament disruption indicative of damaged axons is seen one day after implantation. A marked improvement in the appearance of injury site occurs within the first week, with a significant increase in neuronal density surrounding probes evident at this time point (P≤0.006). NSC-seeding was associated with increased the neuronal density surrounding prostheses in the first week of implantation, with a reversal of this effect at later time points (P<0.05).