Fig. 5.
Expression of CXCR2 in ovarian cancer tissues correlates with a lower cancer patient survival rate. Detection of CXCR2 in ovarian cancer tissues (1–13) compared with normal tissues (14–18) by Western blotting (A). Immunostaining of representative tumor tissues showed low expression and high expression in terms of CXCR2 staining intensity in cancer epithelial cells (400×; B). Overexpression of CXCR2 predicted poor overall (P < 0.001, C) and disease-free (P = 0.003, D) survival of patients with high-grade serous ovarian carcinoma.
