Table 4.

Pathological findings in 12 patients with hypertrophic cardiomyopathy and advanced heart failure

No.	Patient #	Age at death/ transplant (years)	Source	Heart weight (g)	Atrial thrombi	Wall thickness (mm)			LV chamber dilatationa	MB	CAD	Replacement fibrosisb		SVD	Myocyte disarrayb
						VS				LVFW			RV	VS	LVFW
End-stage
1	#4	50	Transplant	520c	n/a	17	17	7	2+	0	0	3+	3+	0	1+
2	#8	55	Autopsy	700	+	23	16	6	1+	+	0	3+	3+	+	3+
3	#5	59	Transplant	500c	n/a	17	13	6	3+	+	+	3+	1+	+	1+
4	#11	63	Transplant	350c	n/a	15	13	4	2+	0	0	3+	3+	0	1+
				517 ± 143
Non-obstructive with preserved systolic function
5	#28	20	Transplant	340c	n/a	15	14	6	1+	0	0	0	0	+	1+
6	#31	34	Autopsy	380	+	20	18	4	1+	+	0	1+	0	+	1+
7	#27	39	Autopsy	440	+	15	12	7	0	0	0	0	0	+	3+
8	#33	53	Autopsy	420	+	16	14	6	0	+	0	1+	0	+	3+
9	#39	60	Transplant	530c	+	17	17	7	0	+	0	0	0	0	1+
10	#43	9	Transplant	120c	n/a	8	8	4	0	+	0	0	0	0	1+
11	#42	12	Transplant	470c	n/a	30	13	7	0	0	0	1+	0	+	3+
12	#45	28	Transplant	370c	n/a	16	12	6	0	+	0	1+	0	+	3+
				384 ± 122

CAD, (atherosclerotic) coronary artery disease; LV, left ventricle; LVFW, left ventricular free wall; MB, myocardial bridge; n/a, not available; RV, right ventricle; SVD, small vessel disease; VS, ventricular septum.

^aLV chamber dilatation semi-quantitatively graded on visual inspection from 0 to 3+ (0, absent; 1+, mild, 2+, moderate; 3+, severe).

^bMyocyte disarray and myocardial replacement fibrosis graded on histological sections semi-quantitatively from 0 to 3+ (0, absent; 1+, mild; 2+, moderate; 3+, severe); +, present; 0, absent.

^cAtria partially or totally missing.