Table 4.
Randomized studies of aprepitant in chemotherapy of highly and moderately emetogenic potential
| Chemotherapy | Patients, n | Complete responsea improvement over control, % | Reference |
|---|---|---|---|
| Cisplatin | 1,043b | 20 (p < 0.001) | [43] |
| Anthracycline | 857 | 9 (p = 0.015) | [44] |
a
Complete response defined as no event of emesis and no administration of rescue medication in the 5-day period following chemotherapy administration [37].
b
Pooled analysis of 2 identical trials of aprepitant in cisplatin-treated patients.