Figure 4.

Misexpression of Math5 and Brn3 factors stimulates cBrn3c expression. Sections from intermediate regions of E11.5 control retinas (A) and retinas infected with RCAS-Math5 (B), RCAS-Brn3a (C), RCAS-Brn3b (D), RCAS-Brn3c (E), or RCAS-Brn3cΔ8 (F) viruses were immunostained with anti-cBrn3c antibody. Misexpressed Math5, Brn3a, Brn3b, and Brn3c caused a significant increase in the number of cBrn3c immunoreactive cells in the ventricular zone, whereas misexpressed Brn3cΔ8 had no effect. (Bar = 25 μm.)