. Author manuscript; available in PMC: 2010 Sep 1.

Published in final edited form as: Antivir Chem Chemother. 2009 Sep 25;20(1):37–46. doi: 10.3851/IMP782

Table 7.

Experimental and model-predicted concentrations of cyclopropavir (5) and “area under the curve” for oral dosing of prodrug (6).

Time, min.	Exp. conc. mg/L	Predicted conc. mg/L	Area under the curve, AUC mg.min/L
20	15.71		157.1
40^*	14.39	14.75	458.1
60^*	10.17	11.94	703.7
120^*	5.10	6.330	1161.8
240^*	2.82	1.780	1637.0
320^*	0.71	0.764	1778.2

Time point included in modeling of the elimination phase.