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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: J Immunol. 2008 Mar 1;180(5):2912–2921. doi: 10.4049/jimmunol.180.5.2912

Figure 8. CD27 signaling is not required for secondary expansion of memory CD8+ T cells.

Figure 8

(A) Expression of CD27 on day 60 NP(366–374)-specific memory CD8+ T cells is equivalent to that of naïve CD8+ T cells. FACS histograms and MFI values shown.

(B) Representative FACS plots indicating percentages of NP-specific CD8+ T cells in the lungs of mice on day 7 post rechallenge; mice were treated on days 0, 2, and 4 post rechallenge with anti-CD27L antibody (right panel) of left untreated (left panel).

(C). Percentages of lung NP(366–374)-specific CD8+ T cells (left panel) and mean (± SEM.) absolute numbers of NP(366–374)-specific CD8+ T cells (right panel) recovered from the lung on day 5 of the secondary immune response, in mice that were treated or not with anti-CD27L antibody. The horizontal line marks the mean of each treatment group. Data pooled from two independent experiments.