Fig 3.

Loss of ER expression in cell projections overlying focally disrupted tumor capsules. Human breast tissue sections from 4 different cases were double immunostained for SMA (red) and ER (brown). Circles identify budding cell projections overlying focally disrupted tumor capsules. Note that although these tumors represent morphologically different subtypes, all the budding cell projections overlying focally disrupted tumor capsules share a very similar immunohistochemical and morphological profile. 100X.