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. 2010 Jun 21;1:38–50. doi: 10.7150/jca.1.38

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Fig 1 — Experimental strategy and tumorigenicity. (A) A flow diagram illustrates the experimental strategy. (B) Human breast cancer cell line MDA-MB-231 formed tumor in athymic nude mice after s.c. inoculation of 5 x 10⁶ cells in athymic nude mice for 2 weeks. (C) MDA/H6 is a MDA-MB-231 derivative cell line that contains a neo-tagged human chromosome 6 and did not form any tumor after the inoculation for 2 months. DEG: differentially expressed gene; TSG: tumor suppressor gene.