Table 1.

Effect of loperamide on feed intake, water intake and fecal properties of constipated rats

Parameters	Normal Control	Constipated rats
Feed intake	15.32 ± 1.12	17.05 ± 0.74 *
Water intake	19.00 ± 1.41	8.92 ± 0.68 **
Number of fecal pellet	64.67 ± 2.80	24.04 ± 0.94**
Water content of fecal pellet	1.52 ± 0.17	0.57 ± 0.10**
Weight of fecal pellet	6.38 ± 0.30	2.95 ± 0.09**

Data are mean ± SD values (n = 4); *not significantly different; ** significantly different from normal control at P < 0.05