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. 2010 Aug 20;11:18. doi: 10.1186/1471-2369-11-18

Figure 1.

Figure 1

Renal artery. Histology demonstrates concentric atherosclerotic plaques in the renal artery of the apoE-/-/LDL-/- double knockout mouse at the age of 80 weeks (A, magnification × 50). Control animals showed no atherosclerotic lesions in the renal artery (B, magnification × 50). In high-power fields, plaque rupture (C, black arrow, magnification × 100) and contrast enhanced Vasa vasorum (D, black arrow, magnification × 100) in the adventitia with large clusters of inflammatory cells occur.