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Histology. Control animals (A, C, E) with normal kidney architecture and regular glomeruli from the cortex (C) and the cortico-medullar junction (E) (PAS stain, A, magnification, ×12.5, C, E, PAS stain, magnification × 100). In contrast, kidneys of apoE-/-/LDL-/- double knockout mice (B, D, F) demonstrate lipoprotein glomerulopathy (D, F) from the cortex (D, PAS stain, magnification × 100) and the cortic-medullar junction (F, PAS stain, magnification × 100).
