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Inhibition of NF-κB p65 nuclear localization by PDTC and BAY 11-7085. The p65 expression in cells were observed using a Leica TCS SP2 confocal microscope. TNFα could promote the rapid nuclear localization of p65. Whereas, TNFα stimulation could not promote the translocation of p65 from the cytoplasm to the nucleus in PDTC- or BAY 11-7085-treated cells.
