Figure 1.
Typical traces showing the changes in diastolic blood pressure, mesenteric and renal blood flow and heart rate induced by i.v. injection of anandamide (3 µmol·kg−1) in a rat anaesthetized with urethane (A) and in a rat anaesthetized with urethane and pithed (B). Arrows indicate drug application. Pithed rats received an i.v. injection of ruthenium red (3 µmol·kg−1) 5 min before anandamide. Note that the small decrease in heart rate in (B) is related to the injection per se, as it occurred identically when the drug vehicle was administered.