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Effect of cisplatin on cannabinoid-1 (CB1) receptor expression and endocannabinoid levels in the kidneys of mice. (A) and (B) show that neither cisplatin nor the treatments indicated influenced CB1 mRNA or protein expression in the kidney 72 h after its administration to mice. (C) depicts cisplatin-induced increased renal anandamide (AEA) but not 2-arachidonoylglycerol (2-AG) levels. Results are mean ± SEM of 6–8 experiments per group. *P < 0.05 versus vehicle.
