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. 2001 Feb 6;98(4):1676–1681. doi: 10.1073/pnas.041416598

Figure 4.

Figure 4

Increased radiation survival in AT cells upon forced expression of IGF-IR. (A) Western blot analysis of IGF-IR expression in GM5849 cells, which lack ATM, and in GM5849 subclones transfected with a plasmid-expressing IGF-IR driven by a viral promoter. (B) Clonogenic survival after exposure to IR of subclones 3 (5849cI3) and 7 (5849cI7), both of which were judged by Western blot in A to express increased levels of IGF-IR, in comparison with the parental 5849 AT mutant cells and to an unrelated wild-type cell line, 637.