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Incremental AUC for PSglu (a, b), forearm glucose uptake (c, d) and forearm blood flow (e, f) in healthy controls (a, c, e) and patients with type 2 diabetes (b, d, f) following placebo (white circles/bars) or tadalafil 20 mg (black circles/bars). All negative incremental AUC values were set to zero, leaving means above zero in bar graph insets. *p < 0.05 compared with placebo
