Table 1.

Effect on vertebral fracture rates (from randomized controlled trials)

	Osteopenia	Osteoporosis (without prevalent vertebral fractures)	Established osteoporosis (with prevalent vertebral fractures)
Raloxifene	●	■	■
Alendronate	NA	■	■
Risedronate	NA	●	■
Ibandronate	NA	■	■
Zoledronate	NA	■	■
Teriparatide	NA	NA	■
Strontium ranelate	●	■	■
Denosumab	NA	■	■

NA No evidence available

■ Denotes a preplanned analysis in the entire study population

● Denotes a post hoc analysis