Table 2.
Metabolic, lipid, and hormonal profiles in women with polycystic ovary syndrome and healthy controls.
| Variables | Control (n=40) | PCOS (n=50) |
|---|---|---|
| Fasting plasma glucose (mg/dL) | 77.3 (3.2) | 82.0 (3.6) ns |
| Fasting insulin (pIU/mL) | 14.2 (1.2) | 25.3 (1.3)a |
| Glucose/insulin ratio | 4.9 (0.22) | 3.3 (0.13)a |
| HOMA-IR | 2.7 (0.11) | 5.1 (0.14)a |
| Triglycerides (mg/dL) | 70.6 (5.3) | 117 (6.4)a |
| Total cholesterol (mg/dL) | 170.3 (8.0) | 198.2 (6.0)a |
| HDL-C (mg/dL) | 46.5 (2.2) | 40.3 (1.4)a |
| LDL-C (mg/dL) | 100.6 (4.1) | 135 (4.3)a |
| VLDL-C (mg/dL) | 21.4 (1.0) | 26.6 (1.1)a |
| Luteinizing hormone (IU/L) | 5.6 (1.02) | 9.8 (1.05)a |
| Follicle stimulating hormone (IU/L) | 6.12 (1.3) | 4.7 (1.2) ns |
| Luteinizing hormone/Follicle stimulating hormone ratio | 0.91 (0.11) | 2.08 (0.14)a |
| Testosterone (ng/dL) | 33.2 (3.1) | 76.9 (5.3)a |
| SHBG (nmol/L) | 55.3 (2.8) | 40.2 (2.6)a |
| Free androgen index (%) | 2.08 (0.12) | 6.63 (1.3)a |
| 17-OHP (mg/dL) | 2.1 (0.13) | 3.2 (0.11)a |
Data are expressed as means (SEM).
PCOS: polycystic ovary syndrome; HDL: high high density lipoprotein; LDL: low low density lipoprotein; VLDL: very very low density lipoprotein;
SHBG: Sex hormone-binding globulin; 17-OHP: 17-hydroxy progesterone.
HOMA-IR: [glucose (in mg/dL×0.05551)×insulin (in μmIU/mL)l]/22.5; FAI=testosterone (nmol/L)/SHBG (nmol/L)×100.
a
Significantly different from healthy control (P< .01); ns: non-significant.