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. 1959 May;38(5):720–729. doi: 10.1172/JCI103852

CALCULATION OF INTRACELLULAR pH FROM THE DISTRIBUTION OF 5,5-DIMETHYL-2,4-OXAZOLIDINEDIONE (DMO). APPLICATION TO SKELETAL MUSCLE OF THE DOG*

William J Waddell 1, Thomas C Butler 1
PMCID: PMC293216  PMID: 13654506

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BUTLER T. C., MAHAFFEE D., MAHAFFEE C. Metabolic demethylation of 3, 5, 5-trimethyl-2, 4-oxazolidinedione (trimethadione, tridione). Proc Soc Exp Biol Med. 1952 Nov;81(2):450–452. doi: 10.3181/00379727-81-19907. [DOI] [PubMed] [Google Scholar]
  2. BUTLER T. C. Quantitative studies of the demethylation of trimethadione (tridione). J Pharmacol Exp Ther. 1953 May;108(1):11–17. [PubMed] [Google Scholar]
  3. CONWAY E. J., DOWNEY M. pH values of the yeast cell. Biochem J. 1950 Sep;47(3):355–360. doi: 10.1042/bj0470355. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. CONWAY E. J. Nature and significance of concentration relations of potassium and sodium ions in skeletal muscle. Physiol Rev. 1957 Jan;37(1):84–132. doi: 10.1152/physrev.1957.37.1.84. [DOI] [PubMed] [Google Scholar]
  5. Conway E. J., Fearon P. J. The acid-labile CO(2) in mammalian muscle and the pH of the muscle fibre. J Physiol. 1944 Dec 15;103(3):274–289. doi: 10.1113/jphysiol.1944.sp004076. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. DEANE N., SMITH H. W. The apparent first dissociation constant, pK1, of carbonic acid in the human erythrocyte. J Biol Chem. 1957 Jul;227(1):101–106. [PubMed] [Google Scholar]
  7. HILL A. V. The influence of the external medium on the internal pH of muscle. Proc R Soc Lond B Biol Sci. 1955 Aug 16;144(914):1–22. doi: 10.1098/rspb.1955.0030. [DOI] [PubMed] [Google Scholar]
  8. MANERY J. F. Water and electrolyte metabolism. Physiol Rev. 1954 Apr;34(2):334–417. doi: 10.1152/physrev.1954.34.2.334. [DOI] [PubMed] [Google Scholar]
  9. NICHOLS G., Jr Serial changes in tissue carbon dioxide content during acute respiratory acidosis. J Clin Invest. 1958 Aug;37(8):1111–1122. doi: 10.1172/JCI103701. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. SCHWARTZ W. B., ORNING K. J., PORTER R. The internal distribution of hydrogen ions with varying degrees of metabolic acidosis. J Clin Invest. 1957 Mar;36(3):373–382. doi: 10.1172/JCI103433. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. SINGER R. B., CLARK J. K., BARKER E. S., CROSLEY A. P., Jr, ELKINTON J. R. The acute effects in man of rapid intravenous infusion of hypertonic sodium bicarbonate solution. I. Changes in acid-base balance and distribution of the excess buffer base. Medicine (Baltimore) 1955 Feb;34(1):51–95. doi: 10.1097/00005792-195502000-00003. [DOI] [PubMed] [Google Scholar]
  12. SWAN R. C., AXELROD D. R., SEIP M., PITTS R. F. Distribution of sodium bicarbonate infused into nephrectomized dogs. J Clin Invest. 1955 Dec;34(12):1795–1801. doi: 10.1172/JCI103234. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. SWAN R. C., PITTS R. F. Neutralization of infused acid by nephrectomized dogs. J Clin Invest. 1955 Feb;34(2):205–212. doi: 10.1172/JCI103073. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. TOBIN R. B. Plasma, extracellular and muscle electrolyte responses to acute metabolic acidosis. Am J Physiol. 1956 Jul;186(1):131–138. doi: 10.1152/ajplegacy.1956.186.1.131. [DOI] [PubMed] [Google Scholar]
  15. WADDELL W. J., BUTLER T. C. Renal excretion of 5,5-dimethyl-2-4-oxazolidinedione (product of demethylation of trimethadione. Proc Soc Exp Biol Med. 1957 Dec;96(3):563–565. doi: 10.3181/00379727-96-23540. [DOI] [PubMed] [Google Scholar]
  16. WADDELL W. J., BUTLER T. C. The distribution and excretion of phenobarbital. J Clin Invest. 1957 Aug;36(8):1217–1226. doi: 10.1172/JCI103518. [DOI] [PMC free article] [PubMed] [Google Scholar]

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