Figure 3.

Effect of an anti-CD8 antibody on the cytolytic activity of a CD8⁺ 2C CTL clone (L3.100). T cells were incubated with ⁵¹Cr-labeled target cells at a 5:1 ratio for 4 h. (A) Lysis of allogeneic target cells (T2-L^d) in the presence of various concentrations of QL9 peptide, in the absence or presence of anti-CD8 antibody 2.43 at 50 μg/ml. (B) Lysis of syngeneic targets cells (T2-K^b) in the presence of various concentrations of SYRGL peptide and in the absence or presence of antibody 2.43 at 50 μg/ml.