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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Nat Genet. 2010 Mar 7;42(4):343–347. doi: 10.1038/ng.545

Figure 2. qPCR validation of the nucleosomes stabilized-destabilized around AR binding sites.

Figure 2

(a) Five AR binding sites near the genes TMPRSS2, STK39, KLK3, TMC6 and TRIM35. “AR ChIP-chip” represents the AR ChIP-chip signals; “H3K4me2 Veh” and “H3K4me2 4h” represent H3K4me2 ChIP-Seq signals before and after 4 hours of DHT treatment. “Input 4h/Veh” represents the qPCR assay of nucleosome fold change for DHT treatment relative to vehicle; “H3K4me2 4h/Veh” represents the qPCR assay of fold change for H3K4me2 signal for DHT treatment relative to vehicle, standard deviation is shown. Each horizontal bar represents a NPS peak region. (b) Detailed qPCR analysis of the AR binding sites near the genes TMPRSS2 and TMC6. Each horizontal bar represents a qPCR amplification region.