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. 2010 Aug 24;1(3):e00131-10. doi: 10.1128/mBio.00131-10

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Copyright © 2010 Smith and Chapman.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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FIG 1 — Protein location in E. coli is indicative of synthetic cost. (A) Each protein in E. coli is plotted based upon its average synthetic cost (ASC) and cellular location. Dotted line, mean ASC of all proteins in E. coli; black bars, mean ASC of proteins in that location; aa, amino acid. U tests were used to compare the protein ASCs of each location against those of cytoplasmic proteins. (B) Locations of all proteins, the 100 most economical proteins, and the 100 least economical proteins in E. coli, as ranked by ASC. OM, outer membrane; IM, inner membrane. (C) Histogram of the percent Gly plus Ser for all proteins in E. coli.