Table 2.
Frataxin-Binding Proteins and Their Functions
| Frataxin | Binding protein | Function | Reference |
|---|---|---|---|
| Mouse frataxin | Mitochondrial processing peptidase beta | Protein processing | 167 |
| Rat frataxin | Aconitase | Citric cycle | 29 |
| Human frataxin | Ferrochelatase | Heme synthesis | 331 |
| Human frataxin | Succinate dehydrogenase | Electron transport chain | 106a |
| Human frataxin | Mortalin/GRP45 | Iron-sulfur cluster biogenesis | 275a |
| Human frataxin | ISD 11(Nfs1/Isul) | Iron-sulfur cluster biogenesis | 275a |
| Yeast frataxin | (Hem15P) ferrochelatase | Heme biogenesis | 181 |
| Yeast frataxin | Succinate dehydrogenase | Electron transport chain | 106a |
| Yeast frataxin | Isul/Nfs1 | Iron-sulfur cluster biogenesis | 102 |
| Yeast frataxin | yfh1 (yeast frataxin) | Frataxin oligomerization | 2 |