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Loss of TLR3 alters hippocampal structure. (A) TLR3 is expressed in the CA1 in adult TLR3+/+ mice. (B–E) Cortical thickness (B), hippocampal volume (C and D), and hippocampal perimeter (E) were similar in TLR3+/+ (n = 6) and TLR3−/− (n = 6) mice. (F) TLR3−/− mice exhibit increased DG and CA1 volumes.
