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. 2010 Aug 16;107(35):15391–15396. doi: 10.1073/pnas.1007953107

Fig. 1.

Fig. 1.

Role of CmlA in the chloramphenicol biosynthesis pathway. Proposed overall scheme for chloramphenicol biosynthesis in S. venezuelae from the L-PAPA precursor. CmlA is proposed to catalyze β-hydroxylation of L-PAPA after it is covalently bound to the T domain of CmlP by a thioester linkage.