TABLE 1.
Definition of Terms
| Term | Definition |
|---|---|
| m | number of mutations per culture |
| μ | mutation rate = probability of mutation per cell per division or generation |
| r | observed number of mutants in a culture |
| r̄ | mean number of mutants in a culture |
| r̃ | median number of mutants in a culture |
| p0 | proportion of cultures without mutants |
| pr | proportion of cultures with r mutants |
| Pr | proportion of cultures with r or more mutants |
| C | number of cultures in experiment |
| N0 | initial number of cells in a culture = the inoculum |
| Nt | final number of cells in a culture |
| Q1 | value of r at 25% of the ranked series of r |
| Q2 | value of r at 50% of the ranked series of r = the median |
| Q3 | value at of r at 75% of the ranked series of r |
| S | sum in Eq. [11], Table 2 |
| a | 11.6 (in Lea–Coulson equations) |
| b | 4.5 (in Lea–Coulson equations) |
| c | 2.02 (in Lea–Coulson equations) |
| ln | natural logarithm (to the base e) |
| f | mutant fraction or frequency = r/N |
| z | dilution factor or sample of a culture plated |