TABLE 4.

Evaluation of the Methods with Experimental Data

Description of the Experiments							m = Number of Mutations per Culture
Exp	Mutant	Cultures	Jackpots	Zeros	Mean	Median	Method	1	2	3	4	5	7	8
	phenotype								LD	LC	Drake	Jones	LC,	MSS,
								p0	mean	median	median	median	ML	ML
1	Lac+	60	2	49	24	0	m	0.20	4.38	0.29	1.00	UD	UD	0.20
							−95%CL	0.10		NA				0.11
							+95%CL	0.36		NA				0.31
2	Lac+	52	0	11	1.9	1	m	1.55	0.57	0.89	1.77	0.84	0.87	1.11
							−95%CL	1.06		0.89				0.77
							+95%CL	2.20		1.32				1.49
3	RifR	20	2	1	12.6	5.5	m	3.00	3.06	2.54	4.00	2.32	2.9	2.9
							−95%CL	1.40		1.70				1.90
							+95%CL	6.67		4.94				4.10
4	RifR	16	1	0	100	37.5	m	NA	17.7	10.4	14.2	9.2	11.2	11.0
							−95%CL			7.6				8.1
							+95%CL			17.0				14.2
5	Lac+	30	1	13	2	1	m	0.84	0.67	0.89	1.77	0.84	0.44	0.71
							−95%CL	0.47		0.29				0.39
							+95%CL	1.37		0.89				1.09
6	Lac+	30	3	6	15.3	1.5	m	1.61	3.32	1.14	2.08	1.04	1.04	1.23
							−95%CL	0.96		0.89				0.76
							+95%CL	2.56		1.69				1.77
5&6	Lac+	60	4	19	8.6	1	m	1.15	1.84	0.89	1.77	0.84	0.72	0.95
							−95%CL	0.80		0.89				0.67
							+95%CL	1.59		1.32				1.27

UD = undefined; NA = not applicable; CL = Confidence limits. Lac⁺ = the ability to utilize lactose; Ril^R = resistance to rifampicin.