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. 2010 Sep 2;6(9):e1001087. doi: 10.1371/journal.pgen.1001087

Figure 3. Expression of Arctic Aβ42 specifically in the adult nervous system shortens lifespan.

Figure 3

Lifespans were determined as described in materials & methods. Survival curves are depicted and data were compared using the log-rank test. P<0.01 comparing median lifespan of UAS-ArcAβ42/+;elavGS/+ +RU flies to their −RU controls. P<0.01 comparing UAS-ArcAβ42/+;elavGS/+ +RU flies to UAS-Aβ40/+;elavGS/+ +RU controls. Induction of Aβ40 in the adult nervous system did not alter lifespan in comparison to non-RU486-treated controls.