Table 1. Cell cycle-related genes identified as at least 2-fold regulated after BCL11B overexpression in Jurkat cells using Affymetrix Arrays and confirmed by quantitative RT-PCR in independent experiment in two different cellular systems.
Symbol | Name | Fold change (Affymetrix Array) | Fold Change (qRT-PCR) in Jurkat | Fold Change (qRT-PCR) in huT-78 |
MYCN | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | −2.0 | −2.4 | −3.3 |
BCL6 | B-cell CLL/ Lymphoma 6 | 3.0 | 3.7 | 2.5 |
CCNG2 | Cyclin G2 | 2.9 | 2.4 | 4.7 |
CDKN1C | Cyclin-dependent kinase inhibitor 1C | 2.1 | 3.5 | 2.7 |
CDKN2C | Cyclin-dependent kinase inhibitor 2C | 2.1 | 3.8 | 3.0 |
HBP1 | HMG-box transcription factor 1 | 2.6 | 2.7 | 2.2 |
TP53INP1 | Tumor protein p53 inducible nuclear protein 1 | 8.0 | 6.4 | 5.2 |