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. Author manuscript; available in PMC: 2011 Sep 7.
Published in final edited form as: Biochemistry. 2010 Sep 7;49(35):7563–7571. doi: 10.1021/bi100744r

Table 2.

Rate constants from global analysis of tryptophan hydroxylase rapid-reaction kinetics with phenylalanine as substrate

kinetic parametera valueb confidence intervala
k1, μM−1s−1 0.281 0.23 – 0.38
k2, s−1 1.8 1.4 – 2.7
k3, s−1 0.39 0.34 – 0.43
a

See Scheme 8.

b

Confidence intervals calculated using the FitSpace option in KinTek Explorer (36, 37).