Figure 1.

Effects of intravitreal caspofungin on the ERG flash response. Representative ERG responses subjects injected with intravitreal balanced salt solution or various doses of C+balanced salt solution to brief flashes of increasing stimulus energies, as indicated, for the fully dark-adapted condition. Black traces, left: representative intravitreal balanced salt solution–injected subject; gray traces, representative C+balanced salt solution–injected subjects; the intravitreal concentrations of caspofungin are indicated below each column of corresponding ERG traces. Unlabeled single and double arrows: reduced a- and b-waves, respectively, for a saturating flash of 2.3 log sc td s for the 41-μM concentration of caspofungin.