Skip to main content
PMC home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1959 Sep;38(9):1498–1508. doi: 10.1172/JCI103928

PERSISTENCE OF ANTIBIOTICS IN BLOOD OF PATIENTS WITH ACUTE RENAL FAILURE. II. CHLORAMPHENICOL AND ITS METABOLIC PRODUCTS IN THE BLOOD OF PATIENTS WITH SEVERE RENAL DISEASE OR HEPATIC CIRRHOSIS*,†

Calvin M Kunin 1,2,‡, Anthony J Glazko 1,2,§, Maxwell Finland 1,2
PMCID: PMC293281  PMID: 14412753

Full text

PDF
1500

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BARNETT H. L. Kidney function in young infants. Pediatrics. 1950 Feb;5(2):171–179. [PubMed] [Google Scholar]
  2. BARNIVILLE H. T., MISK R. Urinary glucuronic acid excretion in liver disease and the effect of a salicylamide load. Br Med J. 1959 Feb 7;1(5118):337–340. doi: 10.1136/bmj.1.5118.337. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BRADLEY S. E., BRADLEY G. P., TYSON C. J., CURRY J. J., BLAKE W. D. Renal function in renal diseases. Am J Med. 1950 Dec;9(6):766–798. doi: 10.1016/0002-9343(50)90292-0. [DOI] [PubMed] [Google Scholar]
  4. BROWN A. K., ZUELZER W. W. Studies on the neonatal development of the glucuronide conjugating system. J Clin Invest. 1958 Mar;37(3):332–340. doi: 10.1172/JCI103613. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. CHITTENDEN G. E., SHARP E. A. The treatment of bacillary urinary infections with chloromycetin. J Urol. 1949 Nov;62(5):771–790. doi: 10.1016/S0022-5347(17)69002-5. [DOI] [PubMed] [Google Scholar]
  6. CLAUDON D. B., HOLBROOK A. A. Fatal aplastic anemia associated with chloramphenicol (chloromycetin) therapy; report of two cases. J Am Med Assoc. 1952 Jul 5;149(10):912–914. doi: 10.1001/jama.1952.02930270006002. [DOI] [PubMed] [Google Scholar]
  7. CORTE G., JOHNSON W. Effect of N-acetyl-para-aminophenol on plasma levels of 17-hydroxycorticosteroids. Proc Soc Exp Biol Med. 1958 Apr;97(4):751–755. doi: 10.3181/00379727-97-23869. [DOI] [PubMed] [Google Scholar]
  8. ERSLEV A. Hematopoietic depression induced by chloromycetin. Blood. 1953 Feb;8(2):170–174. [PubMed] [Google Scholar]
  9. GLAZKO A. J., DILL W. A., WOLF L. M. Observations on the metabolic disposition of chloramphenicol (chloromycetin) in the rat. J Pharmacol Exp Ther. 1952 Apr;104(4):452–458. [PubMed] [Google Scholar]
  10. GLAZKO A. J., WOLF L. M., DILL W. A. Distribution of chloramphenicol (chloromycetin) and its metabolic products between human red cells and plasma. Proc Soc Exp Biol Med. 1949 Dec;72(3):602–604. doi: 10.3181/00379727-72-17512. [DOI] [PubMed] [Google Scholar]
  11. HARGRAVES M. M., MILLS S. D., HECK F. J. Aplastic anemia associated with administration of chloramphenicol. J Am Med Assoc. 1952 Aug 2;119(14):1293–1300. doi: 10.1001/jama.1952.02930310029007. [DOI] [PubMed] [Google Scholar]
  12. JOSLYN D. A., GALBRAITH M. A turbidimetric method for the assay of antibiotics. J Bacteriol. 1950 Jun;59(6):711–716. doi: 10.1128/jb.59.6.711-716.1950. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. KUNIN C. M., FINLAND M. Demethylchlortetracycline; a new tetracycline antibiotic that yields greater and more sustained antibacterial activity. N Engl J Med. 1958 Nov 20;259(21):999–1005. doi: 10.1056/NEJM195811202592102. [DOI] [PubMed] [Google Scholar]
  14. KUNIN C. M., FINLAND M. Persistence of antibiotics in blood of patients with acute renal failure. III. Penicillin, streptomycin, erythromycin and kanamycin. J Clin Invest. 1959 Sep;38:1509–1519. doi: 10.1172/JCI103929. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. KUNIN C. M., REES S. B., MERRILL J. P., FINLAND M. Persistence of antibiotics in blood of patients with acute renal failure. I. Tetracycline and chlortetracycline. J Clin Invest. 1959 Sep;38:1487–1497. doi: 10.1172/JCI103927. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. RICH M. L., RITTERHOFF R. J., HOFFMANN R. J. A fatal case of aplastic anemia following chloramphenicol (chloromycetin) therapy. Ann Intern Med. 1950 Dec;33(6):1459–1467. doi: 10.7326/0003-4819-33-6-1459. [DOI] [PubMed] [Google Scholar]
  17. RUBIN D., WEISBERGER A. S., BOTTI R. E., STORAASLI J. P. Changes in iron metabolism in early chloramphenicol toxicity. J Clin Invest. 1958 Sep;37(9):1286–1292. doi: 10.1172/JCI103716. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. SCHMID R., AXELROD J., HAMMAKER L., SWARM R. L. Congenital jaundice in rats, due to a defect in glucuronide formation. J Clin Invest. 1958 Aug;37(8):1123–1130. doi: 10.1172/JCI103702. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. SCHMID R., HAMMAKER L. Glucuronide formation in patients with constitutional hepatic dysfunction (Gilbert's disease). N Engl J Med. 1959 Jun 25;260(26):1310–1314. doi: 10.1056/NEJM195906252602603. [DOI] [PubMed] [Google Scholar]
  20. SCHMID R. Jaundice and bilirubin metabolism. AMA Arch Intern Med. 1958 Mar;101(3):669–674. doi: 10.1001/archinte.1958.00260150157022. [DOI] [PubMed] [Google Scholar]
  21. SMILEY R. K., CARTWRIGHT G. E., WINTROBE M. M. Fatal aplastic anemia following chloramphenicol (chloromycetin) administration. J Am Med Assoc. 1952 Jul 5;149(10):914–918. doi: 10.1001/jama.1952.02930270008003. [DOI] [PubMed] [Google Scholar]
  22. SMITH G. N., WORREL C. S. The decomposition of chloromycetin (chloramphenicol) by microorganisms. Arch Biochem. 1950 Sep;28(2):232–241. [PubMed] [Google Scholar]
  23. Smith R. M., Joslyn D. A., Gruhzit O. M., McLean I. W., Penner M. A., Ehrlich J. Chloromycetin: Biological Studies. J Bacteriol. 1948 Mar;55(3):425–448. [PMC free article] [PubMed] [Google Scholar]
  24. WOODWARD T. E., SMADEL J. E., LEY H. L., Jr Chloramphenicol and other antibiotics in the treatment of typhoid fever and typhoid carriers. J Clin Invest. 1950 Jan;29(1):87–99. doi: 10.1172/JCI102238. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES