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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Aliment Pharmacol Ther. 2010 Sep;32(5):681–688. doi: 10.1111/j.1365-2036.2010.04391.x

Figure 2. Comparison of rectal pressure-volume relationships and perception before (left panel) and during (right panel) clonidine therapy in a single subject.

Figure 2

Before clonidine, rectal distention induced pronounced balloon volume fluctuations reflecting rectal contractions, culminating in balloon expulsion at 24 mmHg (arrow). After clonidine, rectal contractility was less pronounced and balloon distention was tolerated up to 40 mmHg.